Integration of peroxisomes into an endomembrane system that governs cellular aging
The peroxisome is an organelle that has long been known for its essential roles in oxidation of fatty acids, maintenance of reactive oxygen species (ROS) homeostasis and anaplerotic replenishment of tricarboxylic acid (TCA) cycle intermediates destined for mitochondria.Growing evidence supports the view that these peroxisome-confined metabolic proc